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81.
After studying the velocity and pressure fields inside bipolar plates with different geometries, the analysis has been extended to include the gas passage across the backing or gas diffusion layer (GDL). The gas flow emerging from the porous layer has been monitored using acetone vapor laser-induced fluorescence. The different configurations tested are a parallel commercial case, a set of parallel diagonal channels, a branching cascade-type, and a serpentine distribution of parallel channel blocks. The experimental results have been compared with the predictions obtained from a computational numerical simulation. This study has served to determine the most suitable topology among the tested ones, and has also revealed that knowing the velocity map inside the bipolar plate may not be sufficient to decide if the gas distribution over the catalyst is going to be homogeneous and if a fuel cell is going to operate in an efficient way.  相似文献   
82.
An accurate procedure to extract contact resistivity from contact resistance measurements made on both D-resistor and L-resistor type Kelvin cross test structures with both upper and lower resistive layers is presented. Through computer simulation it can be shown that the collar effects of both upper and lower layers are additive when both layers have a symmetric geometry. The method is based on the determination of a set of “universal curves” through computer simulation. Using dimensionless variables, these curves can be employed in all experimental conditions, eliminating the need of further simulations  相似文献   
83.
To explore the feasibility and operating limits of arteriovenous extracorporeal CO2 removal (AVCO2R) for support of acute respiratory failure, the authors developed a mathematical model to simulate (AVCO2R), evaluate the effects of several parameters used in its application, and predict the feasibility and necessary conditions for total CO2 removal. The mathematical model incorporated compartments representing blood, pulmonary alveoli, pulmonary capillaries, peripheral tissues and capillaries, and an extracorporeal gas exchange device. The model was validated against an animal model of extracorporeal CO2 removal. This model consisted of anesthetized and mechanically ventilated piglets. An extracorporeal CO2 removal device was placed by cannulation of a femoral artery and vein. Dynamic and steady state measurements of CO2 transfer were made and compared with simulations using the mathematical model. There was good agreement between experimental and simulated data, validating the mathematical model under a variety of conditions. The mathematical model was used to determine operating parameters for total CO2 removal. Relationships between extracorporeal blood flow, device diffusing capacity, and device gas sweep flow were established for CO2 removal at various levels of CO2 production. These simulations indicate that it is possible to achieve total CO2 removal using an extracorporeal shunt fraction of 10%-15% of cardiac output, a device diffusing capacity of 0.5 ml x min(-1) x torr(-1) (kg body weight)(-1), and a gas:blood flow of 5 or greater.  相似文献   
84.
This paper presents recent work concerning a small tiltrotor aircraft with a reduced number of rotors. The design consists of two propellers which can tilt laterally and longitudinally. A model of the full birotor dynamics is provided, and a controller based on the backstepping procedure is synthesized for the purposes of stabilization and trajectory tracking. The proposed control strategy has been tested in simulation  相似文献   
85.
Hearing loss from combined exposures among petroleum refinery workers   总被引:2,自引:0,他引:2  
Seventy-three consecutive cases of childhood acute lymphoblastic leukemia (ALL) diagnosed and managed in Queen Mary Hospital over a 10-year period from 1985 to 1994 were retrospectively analysed for their presenting features and treatment outcome. The 48 boys and 25 girls ranged in age from 0.4 to 14.2 years (median: 4.3 years). Bone and joint pain was a relatively common presenting feature besides fever, hepatosplenomegaly and lymphadenopathy. Immunophenotyping of blast cells showed: 51 B-cell precursor ALL, one B-ALL, 10 T-ALL and three myeloid-antigen positive ALL. Eight cases were unclassified since immunophenotyping had not been performed. Out of the 73 patients, treatment outcome was analysed in 20 cases treated with UKALL-VIII regimen and 28 cases treated with either the UKALL-XI regimen or the Hong Kong Children Cancer Study Group (HKCCSG) protocol which was modelled upon UKALL-XI. Although complete remission rates were similar between the two groups, patients treated with the former regimen that was less intensified suffered more relapses than the latter (56 per cent versus 21 per cent, P = 0.04). There were, however, no significant differences both in event-free survival (38.2 +/- 11.2 per cent versus 71.3 +/- 9.3 per cent, P = 0.12) and overall survival (70.0 +/- 10.2 per cent versus 79.6 +/- 8.3 per cent, P = 0.41) between the two groups at 3 years by long-rank test. With the use of risk-directed therapy and improved supportive care, two-thirds of our patients are able to enjoy long-term event-free survival.  相似文献   
86.
In 2000, the European Union founded a project named ‘RAIL: Reliability centered maintenance approach for the infrastructure and logistics of railway operation’ aimed to study the application of Reliability centered maintenance (RCM) techniques to the railway infrastructure. In this paper, we present the results obtained into the RAIL project, including a RCM methodology adapted to large infrastructure networks and a RCM toolkit to perform the RCM analysis, including cost aspects and maintenance planning guidance. This paper addresses the problem of applying RCM to large scale railway infrastructure networks to achieve an efficient and effective maintenance concept. Railways use nowadays very traditional preventive maintenance (PM) techniques, relying mostly on ‘blind’ periodic inspection and the ‘know-how’ of maintenance staff. RCM was seen as a promising technique from the beginning of the RAIL project because of several factors. First, technical insights obtained were better than the existing, so that several maintenance processes could be revised and adjusted. Second, the interdisciplinary approach used to make the analysis was very enriching and very encouraging for maintenance staff consulted. Third, using the RCM structured approach allowed to achieve well-documented analysis and clear decision diagrams. Our methodology includes some new features to overcome the problems of RCM observed in other projects. As a whole, our methodology and Computerized Maintenance Management Systems have produced two short-term benefits: reduction of time and paperwork because databases and tools are accessible through Internet, and creation of a permanent, accurate, and better collection of information. It will also have some long-term benefits: better PM will increase equipment life and will help to reduce corrective maintenance costs; Production will increase as unscheduled downtime decreases; purchase costs of parts and materials will be reduced; more effective and up-to-date record of inventory/stores reports; and better knowledge of the systems to help the company to chose those systems with the best LCC. The results have been corroborated with the application of our methodology to signal equipment in several railway network sections, as shown in this paper. Because of the successful conclusion of the project, the Spanish railway company (RENFE) and the German railway company (DB A.G.), not only decided to adopt RCM to enhance PM, but they have started a large project to implement Total Preventive Maintenance relying on the implantation of the RCM methodology.  相似文献   
87.
Enterococcal endocarditis accounts for 10% of all bacterial endocardits. The infection progresses in a subacute way and when localized on the aortic valve it has a very poor prognosis since the valve is usually destroyed being death the fatal outcome. We report a case of a patient with infective endocarditis resulting from the implantion of the Enterococcus on the native aortic valve. Nor visk factors or an apparent main gate could be found. The patient was hospitalized after several months of a non especific febrile syndrome. The literature is reviewed. Diagnostic tests and clinical signs are discussed making emphasis on the refractoriness to chemotherapy.  相似文献   
88.
In this paper, we focus on the design and implementation of a controller for a two degree‐of‐freedom system. This system is composed of a small‐scale helicopter which is mounted on a vertical platform. The model is based on Lagrangian formulation and the controller is obtained by classical pole‐placement techniques for the yaw dynamics and adaptive pole‐placement for the altitude dynamics. Experimental results show the performance of such a controller. Copyright © 2004 John Wiley & Sons, Ltd.  相似文献   
89.
90.
Silicon detectors in 3D technology are a candidate for applications in environments requiring an extreme radiation hardness, as in the innermost layers of the detectors at the proposed High-Luminosity LHC. In 3D detectors, the electrodes are made of columns etched into the silicon perpendicular to the surface. This leads to higher electric fields, a smaller depletion voltage and a reduced trapping probability of the charge carriers compared to standard planar detectors. In this article, the signal and the noise of irradiated n-in-p and p-in-n 3D silicon strip detectors are compared. The devices under test have been irradiated up to a fluence of 2×1016 1 MeV neutron equivalent particles per square centimetre (neq/cm2), which corresponds to the fluence expected for the inner pixel detector layers at the High-Luminosity LHC. A relative charge collection efficiency of approximately 70% was obtained even after the highest irradiation fluence with both detector types. The influence of different temperatures on the signal and the noise is investigated and results of annealing measurements are reported.  相似文献   
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